NRAS, NRAS proto-oncogene, GTPase, 4893

N. diseases: 611; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 10 2010 2020
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.020 1.000 2 2012 2020
dbSNP: rs121913250
rs121913250 		0.683 0.440 1 114716127 missense variant C/A;G;T snv
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.020 1.000 2 2012 2020
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs2273267
rs2273267 		0.882 0.080 1 114716848 upstream gene variant A/C;T snv
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs2273267
rs2273267 		0.882 0.080 1 114716848 upstream gene variant A/C;T snv
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		Neoplasms; Nervous System Diseases 0.010 1.000 1 2020 2020
dbSNP: rs2273267
rs2273267 		0.882 0.080 1 114716848 upstream gene variant A/C;T snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs2273267
rs2273267 		0.882 0.080 1 114716848 upstream gene variant A/C;T snv
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		Neoplasms 0.010 1.000 1 2020 2020
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 32 1989 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 30 1989 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0025202
Disease: melanoma
melanoma 		Neoplasms 0.800 1.000 16 2005 2019
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 12 2011 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.100 1.000 11 2011 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.090 1.000 9 2011 2019
dbSNP: rs11554290
rs11554290 		0.583 0.600 1 114713908 missense variant T/A;C;G snv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.020 1.000 2 2018 2019
dbSNP: rs121913237
rs121913237 		0.611 0.560 1 114716126 missense variant C/A;G;T snv 8.0E-06
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.020 1.000 2 2013 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C0205748
Disease: Dysplastic Nevus
Dysplastic Nevus 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519695
rs1057519695 		0.641 0.520 1 114713907 missense variant TT/CA;CC mnv
CUI: C1513734
Disease: Solid/Multicystic Ameloblastoma
Solid/Multicystic Ameloblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1513734
Disease: Solid/Multicystic Ameloblastoma
Solid/Multicystic Ameloblastoma 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1057519834
rs1057519834 		0.658 0.480 1 114713908 missense variant TG/CT mnv
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2019 2019